What is an example of an iso-osmolar contrast media?

Iodixanol, marketed under the brand name Visipaque, is recognized as an iso-osmolar contrast media because it has an osmolality comparable to that of human plasma. This property minimizes the risk of osmotic reactions, making it a safer choice for patients, particularly those with compromised renal function or at higher risk for contrast-induced nephropathy.

Iso-osmolar contrast agents are designed to reduce the potential for adverse reactions when administered, as they create less osmotic stress on cells, which can lead to better patient tolerability during procedures such as computed tomography (CT) scans. Compared to hypo-osmolar and hyper-osmolar contrast media, iso-osmolar agents like iodixanol maintain a balance that helps to ensure patient safety and comfort.

The other contrast agents mentioned either fall into the hypo-osmolar or hyper-osmolar categories. For instance, Iopamidol, Ioversol, and Iohexol generally have lower osmolality than plasma, which can sometimes lead to discomfort or reactions during administration, particularly in sensitive populations.